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Biotransformation scientist

Surrey, Windlesham
Closing date
28 Feb 2024

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Contract Type
Full Time

Job Details

Job title: Biotransformation scientist

Location: Slough, Berkshire

Contract: 12-month FTC.

Pay rate: £20/h.

Are you a drug discovery or analytical scientist looking to specialise in biotransformation? Are you looking to join a global Bio Pharma company and use cutting edge research techniques?

SRG are looking for a Biotransformation scientist to work with a global pharmaceutical client, to join their biotransformation and enzymology group (BT&E) to support across a range of new chemical entities (NCE) from early stage hit identification through to pre & post-clinical evaluation

As part of the BT&E team you will be a laboratory-based scientist with experience in the profiling of the biotransformation pathways of NCEs using LC-High Resolution Mass Spectrometry (HRMS). Additional skills such as with other analytical techniques, in vitro methods and general lab skills would be advantageous. You will enjoy a diverse and dynamic workflow supporting a number of projects whilst interacting with functions outside of BT&E.

Key Responsibilities will include:

  • Generate LC-HRMS metabolite profiling data from the analysis of in vitro & in vivo samples
  • Efficiently generate, report and disseminate data to Biotransformation representatives
  • Design and execute biotransformation-based assays to address key issues
  • Take responsibility for the maintenance of LC-MS systems within the group
  • Develop analytical methods for new chemical modalities

Candidate Requirements:

  • An experienced graduate or post-doctoral scientist (BSc. / MSc. / PhD) in chemistry or biochemistry
  • Previous industrial experience in the area of drug discovery (3+ years)
  • High resolution mass spectrometry and chromatography experience (HPLC, uHPLC, LC-HRMS) of small molecules.
  • An understanding of biotransformation pathways of NCEs
  • Experience in general in vitro lab skills
  • Be able to learn new laboratory skills quickly, demonstrate ability to follow protocols but also to design new experiments with excellent method development skills
  • Autonomous, highly organised with excellent attention to detail
  • Strong communication and a collaborative approach suited to a team working environment

To apply click the link or send your CV

Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.


Every day, we help high-calibre scientists, clinical professionals and engineers of all levels build great careers. We are dedicated to providing the best solutions for the broad-based science community, whether temporary or permanent recruitment, cutting-edge managed solutions, or contract scientific and clinical services through Synergy, our unique CRO.


We have established relationships with world-class leaders and small-scale start-ups alike. Our clients value our in-depth regional knowledge developed through our presence across the UK and Europe, and our national exposure that means we offer jobseekers an unrivalled range of career opportunities.



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