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Upstream Process Development Scientist

Hyper Recruitment Solutions
Industry Competitive
Closing date
14 Jul 2022

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Biochemistry, Biology, Biotechnology
Contract Type
Full Time

Job Details

We are currently looking for a Upstream Process Development Scientist to join a growing Gene Therapy company based in the North London area. As the Upstream Process Development Scientist you will be responsible for developing upstream processes for the production of AAV Viral Vectors for the treatment of chronic and rare diseases.

This position would suite a highly motivated Upstream Development Scientist with experience of developing processes for Biological products to joining a developing company that will offer you the opportunity to develop early stage processes to transition from Pre-clinical to early clinical trial. AAV experience is ideal, but this is not required.


Your duties as the Upstream Process Development Scientist will be varied however the key duties and responsibilities are as follows:

1. Development of Upstream Processes for AAV production including but not limited to, bioreactor-based suspension cell culture, transient transfection and primary recovery.

2. Responsible for the design & execution of development work following QbD principals.

3. Write process descriptions, protocols and experimental procedures including SOPs.

4. Transfer technical processes to external Manufacturing sites.


To be successful in your application to this exciting opportunity as the Upstream Process Development Scientist we are looking to identify the following on your profile and past history:

1. Relevant degree in a Life Sciences discipline (a PhD is not required but beneficial) in addition to experience in a Biotechnology and/or Biopharmaceutical company where you have developed Upstream Processes.

2. Proven industry experience in developing scalable upstream suspension-based manufacturing processes, where you will ideally have experience of Ambr250 or Ambr15 or related equipment.

3. A working knowledge and practical experience with Mammalian Cell Culture is a must have, ideally where you have transiently transfected cell lines for the production of Viral Vectors or AAVs. Antibody and other recombinant proteins are also of interest.

Key Words: Upstream Process Development | USP | Development of Upstream Processes | Mammalian Cell Culture | Cell Culture Development | Viral Vector | AAV | Gene Therapy | Bioprocessing | Bioprocess Development | Scale up | GMP | Biothecnology | Biotherapeutic | Biopharmaceutical |

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer who are certified by Investors in People for talent development. We therefore welcome applications for any interested parties who fulfil the role requirements for this position. HRS is a company exclusively supporting the science and technology sectors, and is made up of a collaboration of recruitment professionals and scientists. We look forward to helping you with your next career moves.


Hyper Recruitment Solutions is a specialist and highly compliant recruitment consultancy dedicated to the Science and Technology sectors.

Hyper Recruitment Solutions (HRS), founded and run by Ricky Martin and in partnership with Lord Alan Sugar, has a wealth of recruitment expertise as well as compliance and commercial awareness. We offer a range of permanent, temporary and contract staff.

Our vision is to provide recruitment solutions which will assist in the improvement and quality of life for all. To do so, HRS will focus on the support of sectors whose primary focus is in making the world a better place. This could be working for a Pharmaceutical company who is developing new and existing therapeutics or an FMCG business who is making the latest consumer products in a sustainable and efficient way. We want to provide a service to those areas of actual need which will have an impact on us all.

We provide services across a broad range of industries including the following specialist sectors:

• Biotechnology
• Pharmaceutical
• Medical Device
• Clinical Research
• Food / FMCG
• Engineering
• Science

With all jobseekers we are looking to form close relationships where we can offer you the most accurate and useful advice. We intend to not only find and present the most ideal career options to you, but we want to provide advice on the entire recruitment process. We are a business who listens and advises and as shown on our website we have a clear ‘candidate commitment’ to ensure your search is in the most professional and capable hands. Some of the key areas we focus on include:

• Quality Assurance (including Qualified Persons)
• Clinical Research (all phases and therapeutic fields)
• Bioinformatics
• Research & Development
• Consumer Insight and Sensory
• Lean and Continuous Improvement
• Engineering (all disciplines)
• Manufacturing, Scale up and Technology Transfer
• Packaging and Sustainability 
• Medical Affairs
• Sales and Business Development
• Information Systems & Technology
• Executive Appointments

HRS has been awarded membership to the REC (Recruitment and Employment Confederation) and APSCo (Association of Professional Staffing Companies). This is to assure all clients and candidates that our processes and practices comply with all relevant government and recruitment industry regulations.

Lord Sugar, Ricky Martin and everyone at HRS look forward to working with you. Please do not hesitate to visit our website or contact us via
Telephone: 02032 255 120

Or any of the social media routes below: 
Linked in
Google +

Find Us
0203 910 2980
Amshold House
Goldings Hill

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