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Medicinal Chemistry Project Leader (Senior Research Associate) (Fixed Term)

University of Cambridge
£42,149 - £53,348
Closing date
12 Jun 2022
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Job Details

DEPARTMENT/LOCATION: C.I.M.R. Division of Translational Medicine


SALARY: £42,149 - £53,348


*Appointment to Senior Research Associate is subject to approval by the Faculty Board of the Cambridge School of Clinical Medicine*

The ALBORADA Drug Discovery Institute (ADDI) is seeking a talented Medicinal Chemistry Project Leader to join its team.

The ADDI is part of a network of world-class Drug Discovery Institutes funded by Alzheimer's Research UK and prosecutes drug discovery projects from target to in vivo proof of concept and beyond for novel targets in the neurodegeneration therapeutic area. This is an exciting opportunity to join this established Institute which is based on the prestigious Cambridge Biomedical Campus.

The successful applicant will have a PhD (or equivalent experience) in a relevant field and extensive experience of drug discovery. Reporting to the Head of Chemistry, they will be responsible for managing multidisciplinary drug discovery teams to meet project objectives. In particular, they will lead medicinal chemists to design and synthesize hits and leads for protein targets with therapeutic potential in neurodegeneration. This may include applying innovative approaches to hit identification as well as devising and implementing strategies to improve biological activity and reduce DMPK liabilities during lead generation and lead optimization. The applicant will have proven experience of working with biology colleagues and leaders to influence project strategy and successfully design cellular and in vivo experiments. The successful applicant will be active in the chemistry lab and have excellent medicinal and synthetic chemistry skills, a flair for problem solving and a history of leadership. They will likely have experience of managing line reports and/or external contractors. Moreover, they will have excellent communication, management and organisational skills, and a willingness to work as part of a team in order to drive forward collaborative projects.

Specific enquiries about the post may be addressed to Steve Andrews (

Fixed term: The funds for this post are available until 31 October 2025 in the first instance.

Research Associate (SRA) level; appointment as an SRA will require evidence of an independent research reputation. Due to the levels of skills and experience required we anticipate making an appointment either on the RA scale or towards the bottom of the SRA scale.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.


Closing date: 12th June 2022

Interview date: to be confirmed


Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference SA30609 on your application and in any correspondence about this vacancy.


The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.


The University has a responsibility to ensure that all employees are eligible to live and work in the UK.



The University of Cambridge is one of the world’s oldest and most successful Universities, with an outstanding reputation for academic achievement and research. It was ranked first in the 2011 QS World University Rankings and its graduates have won more Nobel Prizes than any other university in the world. The University comprises more than 150 departments, faculties, schools and other institutions, plus a central administration and 31 independent and autonomous colleges.

Chemistry in Cambridge aims to support fundamental science of the highest quality in a first class physical environment. The Department includes a large number of internationally recognised research groups covering an exceptionally broad spectrum of chemical science ranging from molecular biology to geophysics. Our enthusiastic research culture embraces new challenging areas, including strong collaborations with other academic disciplines and institutions, while maintaining a powerful presence in the traditional core areas of chemistry.

The Chemistry Department hosts around 200 postdoctoral research staff, over 250 postgraduate students, and around 60 academic staff, including newly independent researchers.

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