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Principal Medicinal Chemist 

Entrust Resource Solutions
Oxford, Oxfordshire
Significant and Negotiable Salary
Closing date
19 Nov 2021

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Job Details

We have an exciting opportunity for a Principal Medicinal Chemist to join our ‘ground-breaking’ client - a young and dynamic biopharmaceutical company.


Using your vast experience within an industrial drug discovery environment and experience with patent applications, as well as your project leadership abilities you will be responsible for:-


  • driving forward medicinal chemistry projects. 
  • co-ordinating synthetic chemistry activities to ensure the delivery of high quality, small molecule development candidates within competitive timeframes. 
  • safeguard intellectual property. 
  • managing CRO’s as well as collaborating with external patent attorneys.


To succeed you will be educated to PhD level; have exceptional knowledge of synthetic and medicinal chemistries supplemented by a solid understanding of biological signalling pathways, structure-based drug design and ADME optimisation in drug discovery.  You will also be experienced in all stages of the interdisciplinary drug discovery process and a background in oncology and/or immunology would be highly advantageous.


For more information, please contact Andy Cuthbert on 01606 818295 or email


Entrust Resource Solutions (ERS) is a resourcing group comprising of three like-minded consultancies operating within the life sciences, healthcare and technology industries Globally. – Entrust People Ltd – Horton International UK Ltd – SCI Search and Selection Ltd

Finding the best talent in the market is critical to the growth and ongoing improvement of every business. We help our clients navigate talent demands from bench to board with our tailored search and resourcing solutions. With our in-house knowledge of the life sciences industry, we have developed a consultative, proactive and creative recruitment solution for our clients across the UK, Europe & US. We tailor our strategy to best suit the needs of each individual client, working with them to understand their current and future growth plans. 

We specialise in the following disciplines across UK wide Life Science / scientific sectors :-

  • Research and Development - Analytical Chemistry, Toxicology, Drug Discovery, Formulation, Process Chemistry, Quality, Validation, Project Management, Synthetic / Organic Chemistry
  • Pharmaceutical Development - Clinical Development, Clinical Operations, Medical Quality, Data Management, Regulatory Affairs, Safety, Bio Statistics
  • Technical Support - Manufacturing, Engineering, Supply Chain, Quality Assurance, Quality Control, GMP Operations
  • Commercial - Manufacturing, Engineering, Supply Chain, Quality Assurance, Quality Control, GMP Ops

Our talented team of scientists and life science experts have a wealth of experience across the UK and European markets. From our three offices across the UK, we service roles from bench to board, supporting your full hiring needs, including executive search, permanent and contingent talent planning.

We manage the full hiring process, reliably and comprehensively, until a successful placement is made. We offer our clients a first-class service, from understanding your current and future hiring plans and comprehensive candidate searches, to timely and relevant CVs for interview consideration and offer negotiation, all with regular communication on our progress.

For candidates, we offer an unparalleled understanding of their industry and intended career progression, enabling us to secure the best fitting roles available in the industry.

Website : www.

Phone : 01224 907990 / 01606 818290




Find Us
01224 907990 / 01606 818290
Head Office
River Court
5 West Victoria Dock Road
DD1 13JT
United Kingdom
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