Scientist/Senior Scientist - Assay Development

2 days left

Recruiter
CK Group
Location
Cambridge
Salary
Competitive
Posted
22 Apr 2021
Closes
20 May 2021
Ref
50012
Contact
Naynesh Mistry
Sector
Biochemistry
Contract Type
Permanent
Hours
Full Time
CK Group are working in partnership with a growing biotechnology company to recruit a talented Scientist or Senior Scientist with expertise in developing antibody-based assays, to join them at their site based in Cambridge on a permanent basis.

The Company:

An exciting opportunity to join a company that is focused on drug discovery and development for protein misfolding diseases. Based in Cambridge, they offer a competitive salary, bonus, pension and health cover.

Scientist/Senior Scientist Role:
  • Assist in running a busy experimental laboratory and contribute to advance the internal research around assay development for toxic oligomer measurements in protein misfolding diseases.
  • Conduct drug discovery research projects.
  • Contribute to the development and application of new methodologies and establishing assays for demonstrating target engagement.

Responsibilities:
  • Use and contribute to the development of antibody-based assays for the direct measurement of protein oligomeric toxic species that are generated during protein aggregation in protein misfolding diseases.
  • Develop ELISA and SIMOA-based assays for assessing protein oligomer levels in a range of samples from in vitro, to cells and ex vivo.
  • Contribute to the automation of such assays.

Your Background:
  • A PhD with extensive experience working in protein chemistry, biochemistry, molecular biology or a related discipline.
  • Extensive experience in ELISA and other antibody-based binding/diagnostic assays.
  • Experience in the recombinant expression (in microbial or mammalian systems) and purification of proteins, in particular antibodies, using a variety of chromatography techniques (e.g. AKTA purification systems, HPLC) and their further characterisation using biochemical and biophysical techniques.
  • Experience in assisting to run a busy biophysical, biochemical or molecular biology laboratory.

Apply:
For more information or to apply for this Scientist/Senior Scientist position, please contact Naynesh Mistry on 01246 457703 or email nmistry@ckgroup.co.uk, quoting job ref 50012.

It is essential that applicants hold entitlement to work in the UK.

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