Medicinal Chemist

Belfast (City/Town) (GB)
19 Mar 2021
12 Apr 2021
Contract Type
Full Time
Accreditation Requirements
Not specified

Medicinal Chemist
Hours: 40 hours per week
Salary: Competitive
Ref No: HRJOB6331
Business Unit: Discovery
Location: Belfast
Open To: Internal and external applicants welcome

The Company
Almac Discovery is a research-driven drug discovery company dedicated to the development of novel and innovative approaches to the treatment of diseases of high unmet need (including oncology, muscle-wasting and neurodegeneration) by applying a target-class approach. Our business model is to develop preclinical stage assets which are then licensed to pharmaceutical/biotechnology partners for further development. We also look to collaborate with partners to apply our medicinal chemistry and translational biology expertise to targets of mutual interest. Key research themes include deubiquitinase enzymes (DUBs) and protein drug conjugates

Almac Discovery is one of seven business units within the Almac Group of companies and is located on the Queen’s University Belfast life sciences campus, close to two major hospitals and the Northern Ireland Cancer Centre. We have additional laboratories in Edinburgh (Protein Therapeutics) and offices in Manchester (Bioinformatics).

The Role
Working as an integral member of the Almac Discovery Chemistry team based in Belfast, you will be tasked with creatively and efficiently designing, synthesising and characterising key target compounds with suitable drug-like properties for biological testing. Working on challenging targets from hit-generation through to candidate selection, the role will involve independent design of fit-for-purpose synthetic routes to target molecules that will allow rapid interpretation of project SAR and ultimately will drive projects forward.

The position will suit a self-sufficient and self-motivated synthetic chemist with excellent communication skills and teamworking ability. More broadly, you will proactively work in collaboration with colleagues across scientific disciplines with the aim of creating much needed first-in-class medicines of the future.

We offer a competitive salary and benefits package as well as the chance to work for an innovative R&D company within the global Almac Group.  As well as excellent training and development opportunities, we offer real potential for career progression and much more!

Additional Information
Please note we have both permanent and temporary opportunities available for this role

Essential Criteria

  • BSc (or above) in chemistry/medicinal chemistry
  • An excellent knowledge of modern synthetic organic chemistry

Desirable Criteria
(The following criteria may be applied if a large pool of applicants exist)

  • PhD in synthetic organic chemistry
  • Experience of industrial drug discovery, gained either directly or by working in collaboration with a drug discovery company.

Additional essential and desirable criteria are outlined in the job description and person specification attached to the online job posting

To Apply
Apply online at
Closing Date
12th April 2021 at 1000 hours