Principal Research Scientist

Experience dependent
30 Sep 2020
30 Oct 2020
Georgina Beer
Contract Type
Full Time
We are currently looking for a Principal Research Scientist to join a leading immunotherapy biotechnology company based in the London area. As the Principal Research Scientist in the Gene Engineering team, you will be responsible for leading and implementing the scientific experiments for the research and development of genetically engineered T cells.


Your duties as the Principal Research Scientist will be varied however the key duties and responsibilities are as follows:

1. You will be responsible for the design, planning and delivery of gene engineering experiments, including the expansion and transduction of T cells, as well as exploring all aspects of their immunological function.

2. As the Principal Research Scientist, you will line manage and develop an expanding team. You will help troubleshoot and support the team in the design of CAR and other constructs, as well as supporting the design, plan and delivery of the functional characterisation data of the genetically engineered T cells.

3. It will be your responsibility to lead projects from concept to completion while remaining lab-based.

4. You will have the opportunity to input into and help design preclinical work packages and early process development work plans, while working with multidisciplinary matrix teams.


To be successful in your application to this exciting opportunity as the Principal Research Scientist we are looking to identify the following on your profile and past history:

1. A degree in a relevant science subject (e.g. Immunology, Biotechnology, Biochemistry, Molecular Biology, Cell Biology, etc.) is essential.

2. Proven industry experience in the field of cell therapy, especially CAR-T therapy, is required for your application.

3. A working knowledge and practical experience with primary T cell culture, molecular biology and cloning techniques, as well as vector production will be essential.

Key Words: Gene Engineering | Principal Scientist | Research | R&D | Development | CAR T | T Cell | Cell Therapy | Biotechnology | Immunotherapy | Immunology | Molecular Biology | Cell Biology | Primary Cell Culture | Cloning | rt-qPCR | Flow Cytometry | Vector Production | Assays | Project Lead | Laboratory | CGT

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer who are certified by Investors in People for talent development. We therefore welcome applications for any interested parties who fulfil the role requirements for this position. HRS is a company exclusively supporting the science and technology sectors, and is made up of a collaboration of recruitment professionals and scientists. We look forward to helping you with your next career moves.

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