Senior Scientist, Medicinal Chemistry

Little Chesterford, Saffron Walden
01 Aug 2018
07 Sep 2018
Contract Type
Full Time

Senior Scientist, Medicinal Chemistry

Location: Chesterford Research Park, near Cambridge, UK

Full time, permanent

NodThera is a biotechnology company focused on the discovery and development of new treatments for diseases driven by chronic inflammation.  Having recently secured a £28 million Series A Financing the company is continuing to progress its promising pipeline of compounds.

As a result of an ongoing expansion, NodThera is looking for an exceptional Medicinal Chemist to join a small but growing team.  The successful candidate will make an immediate contribution to the design of compounds and will support other activities associated with advancing the portfolio of potential drug candidates.  This is a tremendous opportunity to join a well-funded biotechnology company operating in a cutting-edge area of research at an important stage in our expansion.


  • Analyse and interpret scientific data from multiple sources, using resulting information to guide the design of future targets and experiments
  • Perform literature and patent searches
  • Draft experimental patent procedures
  • Provide support to synthetic chemistry CROs; ensure smooth progression of targets, troubleshoot reactions and advise on synthetic routes
  • Support other outsourced activities
  • Compile data for and give presentations on Medicinal Chemistry both internally and externally as appropriate               
  • Continually develop scientific knowledge as appropriate to the role and the area of research

Skills and experience required:

  • Relevant educational qualifications (BSc/MSc/PhD in Chemistry, Medicinal Chemistry or a related subject)
  • Minimum five years’ experience in small molecule drug discovery gained in an industrial setting, supported by a track record of publications, patents and presentations
  • Detailed understanding of contemporary small molecule Medicinal Chemistry principles, DMPK, ADMET and pharmacology
  • Skilled in data and SAR analysis and interpretation
  • Track record of significant contribution toward the design of drug-like molecules
  • Excellent interpersonal and communication skills, high attention to detail
  • Strong desire to work in a fast-paced biotech environment, a willingness to be adaptable to the potential of changing roles and responsibilities

To apply for the role please send the following to;

  • CV
  • Covering letter
  • Confirmation of your eligibility to work in the UK (independently of employer sponsorship)

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