Senior Scientist / Technical Leader - Pre-Formulation

West Yorkshire
£26000 to £32000 per annum
11 May 2018
08 Jun 2018
Eve Hegarty
Contract Type
Full Time
We are currently looking for a Senior Scientist / Technical Leader with experience of pharmaceutical pre-formulation to join a growing life sciences company based in the West Yorkshire area.

As the Senior Scientist / Technical Leader - Pre-Formulation you will be responsible for leading drug development projects centring on materials characterisation, solid form optimisation and early-stage formulation development. The role will involve experimental design and data interpretation from a diverse range of solid state and related techniques to optimise pre-formulation strategies e.g. XRD, particle size, surface area / porosity, thermal, DVS, isothermal calorimetry, micronizing and milling techniques, freeze drying, spray drying, blending approaches hot stage and polarised light microscopy.

We welcome applications from candidates with experience in some of the following areas: pre-formulation, pharmaceuticals, pharmaceutical science, API solid form optimisation, salt screening, polymorph screening, crystallisation, excipient compatibility, GMP, GLP, IND, CMC.


Your duties as the Senior Scientist / Technical Leader will be varied however the key duties and responsibilities are as follows:

1. Revenue generating laboratory-based pre-formulation project work, applying diverse techniques to a wide range of sample types and technical challenges. May act as lead scientist or project manager, as required.

2. Managing client programmes focussing on pre-formulation and proof-of-concept early formulation.

3. Associated data interpretation and report writing; peer review of data / reports generated by colleagues.
4. Providing technical guidance to colleagues at on site and more widely across the Group, in the pre-formulation field.

5. Training and mentoring colleagues in own specialist techniques, processes, instruments, providing user support, method and instrument troubleshooting.

6. Within specialist area, advising commercial colleagues on the most appropriate solution to customer problems, including solutions not currently offered by the company.

7. Client liaison, inter-group liaison, internal projects and initiatives.


To be successful in your application to this exciting opportunity as the Senior Scientist / Technical Leader we are looking to identify the following on your profile and past history:

1. Degree / PhD in Pharmaceutical Sciences, Organic Chemistry, Pharmaceutics or related field with demonstrated relevant experience. You will be expected to have experience in at least one of the following fields:

- API solid form optimisation
- Salt / polymorph / crystallisation / excipient compatibility screening
- Aqueous / solvent / biorelevant media solubility assessments

2. Wide-ranging experience in the pharmaceutical industry in small molecule pre-formulation and drug development across a range of delivery routes (oral, parenteral, inhalation etc.) and therapeutic indications.

3. Experience of working in a regulated environment (quality, health and safety, GMP / GLP). You will also be expected to have a familiarity with the drug development regulatory pathway (e.g. IND, CMC requirements).

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer who are certified by Investors in People for our talent development. We welcome applications for any applicant who fulfil the role requirements for this position. HRS is a company exclusively supporting the science and technology sectors, and is made up of a collaboration of recruitment processionals and scientists. We look forward to helping you with your next career moves.