Scientist - Large Molecule Analysis

Location
Cambridgeshire
Salary
Dependent on experience
Posted
13 Sep 2017
Closes
11 Oct 2017
Ref
J3536
Contact
Eve Hegarty
Contract Type
Permanent
Hours
Full Time
We currently have an exciting opportunity for a Scientist - Large Molecule Bioanalysis to join a leading life sciences company based in the Cambridgeshire area. This is a great opportunity for a graduate of experienced scientist to join the large molecule bioanalysis team.

KEY DUTIES AND RESPONSIBILITIES:

Your duties as the Scientist - Large Molecule Bioanalysis will be varied however the key duties and responsibilities are as follows:

1. Undertake bioanalytical laboratory work on behalf of a diverse range of external clients including pharmaceutical and veterinary drug manufacturers.

2. Development and validation of qualitative/quantitative assays and subsequent sample analysis to determine concentrations of drugs, peptides and proteins in biological samples.

3. A diverse range of scientific techniques are used including:

- Enzyme immunoassay, Gyrolab, Mesoscale Discovery (MSD), Singulex Erenna, Radioimmunoassay, AlphaLISA and DELFIA
- Multiplexing technology including MSD and Luminex
- PK analysis of therapeutic biologics
- Immunogenicity testing of biologics
- Biomarker quantification
- Flow cytometry
- Cell-based assays
- Molecular biology including qPCR, Western blotting, electrophoresis and DNA sequencing
- Characterisation and labelling of antibody reagents
- Mass spectrometry e.g. peptide mapping, protein ID and quantification
- Automation of assays and integration into LIMS
- Enzyme activity assays

ROLE REQUIREMENTS:

To be successful in your application to this exciting opportunity as the Scientist - Large Molecule Bioanalysis we are looking to identify the following on your profile and past history:

1. Relevant degree in a biological science, or relevant experience working within a highly regulated life sciences facility, for example GMP or GLP.

2. You will need to demonstrate familiarity with analytical method development / validation. You should have experience with at least some of the following laboratory skills: Enzyme immunoassay, Gyrolab, Mesoscale Discovery (MSD), Singulex Erenna, Radioimmunoassay, AlphaLISA, DELFIA, MSD, Luminex, PK analysis of therapeutic biologics, cell based assays, flow cytometry and mass spectrometry.

Key Words: Enzyme immunoassay | Gyrolab | Mesoscale Discovery (MSD) | Singulex Erenna | Radioimmunoassay | AlphaLISA | DELFIA | Luminex | PK analysis | cell based assays
| flow cytometry | mass spectrometry | Scientist | Large molecules | Biologics | GMP | GLP

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer that is happy to welcome applications for any applicant who fulfil the role requirements for this position. HRS is a company exclusively supporting the science and technology sectors and is made up of a collaboration of scientists supporting science. We look forward to helping you with your next career moves.

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