Medicinal Chemist

Cambridge, UK
16 May 2017
15 Jun 2017
Contract Type
Full Time

Astex Pharmaceuticals is a world leader in innovative drug discovery and development. The company has successfully applied its proprietary Fragment-Based Drug Discovery platform to generate multiple new drug candidates that are progressing in clinical development. Astex continues to grow and focuses on Oncology and Neurological Disorders. We have opportunities at our Cambridge, UK, Research Centre for experienced and innovative scientists, wishing to develop their career in a thriving multidisciplinary, industrial environment


Job Description:

We have an exciting opportunity for a lab-based medicinal chemist keen to work on Fragment Based Drug Discovery (FBDD) in close collaboration with computational chemistry, structural biology, biology and DMPK. Candidates will be highly rigorous scientifically and able to challenge and stimulate colleagues. An excellent knowledge and understanding of synthetic organic chemistry and medicinal chemistry as well as a proven track record and significant practical experience is required. Experience of structure-based design would be an advantage.

Qualifications and Experience:

  • Ph.D. in synthetic organic chemistry with demonstrated expertise in delivering target molecules
  • Several years’ experience in medicinal chemistry including lead optimization
  • Good working knowledge of DMPK and chemistry approaches to problem-solving
  • Outstanding publication record in high impact journals
  • Good interdisciplinary team working and communication skills are essential

We offer excellent training and career development opportunities as well as a highly competitive salary and benefits package.

Closing Date: 15th June 2017

To apply, please send your CV and a cover letter quoting the job reference: MC/052017 to

For information on Astex Pharmaceuticals please visit:
and for information on Otsuka Pharmaceuticals please visit:

We are recruiting for a number of roles some are permanent and some are for 2-3 year fixed term contracts depending on qualifications and experience

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