Bioassay Technical Scientist

Location
Wrexham
Salary
Competitive
Posted
28 Mar 2017
Closes
25 Apr 2017
Ref
J3728
Contact
Eve Hegarty
Contract Type
Permanent
Hours
Full Time
We are currently recruiting for a Bioassay Technical Scientist to join a leading life sciences company based in the North Wales area.

As the Bioassay Technical Scientist you will be responsible for delivery of effective bioassay development and testing to support therapeutic Toxins and other Biological products developed and in-licensed by our client. This is a permanent role.

KEY DUTIES AND RESPONSIBILITIES:

Your duties as the Bioassay Technical Scientist will be varied however the key duties and responsibilities are as follows:

1. Proactive scientific and technical for the design, development and validation of effective fit-for-purpose and robust biological-response bioassay including in vitro cell-based assays, binding and immunoassays and BoNT protease activity assays to effectively support Biologic products developed and in-licensed by our client.

2. Support implementation of bioassay strategies and technologies, performing the development, validation and testing using bioassays that appropriately reflect product mode-of-action in vitro, in support of batch release, stability and product characterisation testing (including support of formulation and bioprocess development/optimisation); from new drug candidate selection, to pre-clinical (pharmacology & toxicology), clinical development, transfer to Manufacturing/QC, and commercial product testing support (e.g. investigations).

3. Support assay validation in accordance with ICH guidelines (to support cGMP testing), and regulatory documentation to support product development plans, briefing documents and CMC documentation, as required.

4. Support effective pre-clinical and clinical development study requirements and the transfer of assays to operations in-house and with third party contractors.

ROLE REQUIREMENTS:

To be successful in your application to this exciting opportunity as the Bioassay Technical Scientist we are looking to identify the following on your profile and past history:

1. Relevant qualification in a life sciences based discipline eg. cell biology, immunology, molecular biology, pharmacology, etc, plus some working experience within an industry, biotech, research or post doc environment.

2. Proven experience with the following laboratory techniques:
- Cell based potency assays
- Aseptic culture of mammalian cell lines suspension and adherent
- Familiarity of working to GXP regulations

3. You will need to demonstrate the right attitude for working in an industrial setting as the role will involve some routine laboratory work. This is a technical role where approximately 80% of your duties will be based in the laboratory.

Key Words: Scientist | Analytical | Cell Based Assay | Bioassay | Potency Assay | Biopharmaceutical Development | Biologics | Immunoassay | Biotherapeutics | Cell Biology | Immunology

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer that is happy to welcome applications for any applicant who fulfil the role requirements for this position. HRS is a company exclusively supporting the science and technology sectors and is made up of a collaboration of scientists supporting science. We look forward to helping you with your next career moves.